In my last post, I provided information on the history of the mechanical CPR device. Today I’ll examine the results of a paper published just two weeks ago that studied the rates of favorable neurological survival and overall survival to discharge in patients treated with this device.
A small group of researchers from St. Luke’s Hospital in Kansas City, Emory University in Atlanta, and the University of Texas Southwestern in Dallas performed this study. It was a seven-year, observational cohort study that used the Cardiac Arrest Registry to Enhance Survival database. This is a prospective, multicenter registry of patients with out-of-hospital cardiac arrest in the U.S. It has a large catchment area of 200 million residents, representing about 60% of the U.S. population.
To evaluate the impact of using a mechanical CPR device for these patients, the agencies evaluated had to have submitted two or more years of data before they started using it. The researchers then evaluated whether introducing the mechanical CPR device was associated with higher survival to discharge or favorable neurological survival.
Here are the factoids:
- The control group consisted of nearly 52,000 patients, involving 73 EMS agencies. They did not adopt the use of the device during the study period. Simple trends over time were studied.
- The study group was 49 agencies with 32,000 patients that did begin using the device.
- Overall favorable neurologic survival ranged from 9.6% to 10.6%, and survival to discharge ranged from 11.1% to 12.0% in the control group. These were not significant differences. It suggests there was no long-term change in these rates due to other factors.
- In the study group, favorable neurologic survival was 8.9% before mechanical CPR device use, and 8.3% after. This was not a significant difference.
- Also in the study group, survival to discharge was 11.0% before and 10.0% after. This was not a significant difference.
- There were no improved outcomes between agencies that used the devices heavily, or if 911-witnessed arrests were included.
The authors concluded that EMS agency rates of favorable neurologic survival and survival to discharge were not any higher at agencies that started using mechanical CPR devices.
Bottom line: This study shows no improvement in two kinds of survival among patients treated by EMS agencies that adopted the mechanical CPR device. It did not evaluate the quality of the CPR applied. However, this is implied in the reason for using this device and the marketing materials provided by the manufacturers.
This paper provides strike one for using the mechanical CPR device to improve survival. In my next post, I’ll review several smaller randomized clinical trials looking at the impact of these devices. Then I’ll finish up with an analysis of a Cochrane Systematic Review on the benefit of this device.
Reference: Mechanical CPR Device Use and Cardiac Arrest Survival in EMS Agencies. Circulation. 2026 Aug 11;154(6):532-541. doi: 10.1161/CIRCULATIONAHA.126.079272. Epub 2026 Jun 18. PMID: 42312381; PMCID: PMC13286238.




