Tag Archives: protocol

Abdomen, Solid organ

Use Of A Solid Organ Injury Protocol For Pediatrics

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Kids are frequent flyers when it comes to abdominal injury, with about 15% of their injuries involving this anatomic area. Solid organ injuries, mainly the liver and spleen, are the most prevalent ones. The American Pediatric Surgical Association (APSA) published a practice guideline way back in 2000 that outlined a consistent way to care for children with solid organ injuries.

Unfortunately, they were very conservative, recommending days of bedrest, extended NPO status, very frequent blood draws, and a lengthy hospital stay. Many hospitals, including mine, developed less conservative management routines, noting that children nearly always tolerate liver and spleen injury better than adults.

The trauma group at Vanderbilt modified the APSA guidelines and, more recently, made additional changes based on a new algorithm released by the organization. This new guideline moved away from organ injury grade-based factors and embraced hemodynamic status as the overall guide to care. The Vanderbilt group performed a retrospective study comparing hospital and ICU length of stay, patient costs, readmission, and death rates using the two guidelines.

Under the old protocol, grade I-III injuries were admitted to a floor bed and higher grades to an ICU at the discretion of the surgeon. The minimum hospital stay was, at minimum, the organ injury grade. Children were kept NPO overnight and placed on bed rest for nearly one day per injury grade.

With the new protocol, children were admitted to the floor if their vital signs normalized after volume resuscitation.  Hematocrit was obtained on admission and possibly again after 6 hours, then only repeated if < 21 or a change in vitals was noted. There were no diet or activity restrictions. Children with abnormal vital signs after volume were admitted to the ICU and kept on bed rest until they normalized. Labs were drawn regularly. Length of stay was based on meeting pain control, diet, and activity goals.

Here are the factoids:

  • There were 176 children (age < 18) enrolled in the old protocol during a four-year period and 170 in the new protocol over 3.5 years
  • Both groups were similar demographically and in injury grade and ISS
  • ICU length of stay was “significantly” shorter under the new protocol (.54 vs .78 days)
  • Hospital length of stay was also “significantly” shorter (2.9 vs 3.5 days)
  • Inflation-adjusted costs were slightly higher under the new protocol ($68,042 vs $65,437) even though the authors claim the opposite in the abstract once injury grade and ISS are factored in
  • Survival was the same at 99.4%
  • Readmission rates were significantly higher under the new protocol (7.1% vs 2.3%)

The authors’ conclusions parroted these results and recommended larger studies to detail any cost advantage and identify the cause for the difference in readmission rates.

Bottom line: This study leaves a lot to be desired. The authors’ definition of “pediatric” is age < 18. As we all know, there is a big difference in “kids” who are pre- vs post-puberty. The good news is that the mean and median ages are about 11 in the study, so there should be fewer older “kids” to cause interference.

The authors reported hazard ratios for the lengths of stay, which were statistically significantly different. However, their clinical significance is in doubt. A difference of 6 ICU hours? Or two-thirds of a hospital day? I’m not impressed. 

Cost differences are basically a wash, and a deep read of the paper shows that many kids did not have an isolated solid organ injury. Non-abdominal injuries could have an Abbreviated Injury Scale score of up to 3. It is easy to imagine that these could impact both length of stay and cost.  

Finally, the readmission rates include many problems related to non-abdominal injuries, including the thorax, soft tissues, and even an epidural hematoma. After excluding these non-abdominal complications, the numbers for both protocols are so low it’s hard to believe that a good significance test can be performed.

The authors’ conclusions are correct: more work needs to be done. This paper doesn’t really teach us much since all the conclusions are extremely weak. A much better, prospective, multicenter trial should be performed. Unfortunately, getting buy-in from multiple centers/surgeons to use the same protocol in children is hard.

But with all that being said, there is no reason you can’t adopt something similar to the new protocol at your center. My own experience has shown that a more aggressive guideline gets kids home sooner and healthier and that there is no difference in readmission rates. I just need a bunch of other surgeons to duplicate these results and write them up!

Reference: A Protocol Driven Approach to Reduce Lengths of Stay for Pediatric Blunt Liver and Spleen Injury Patients. Journal of Trauma and Acute Care Surgery ():10.1097/TA.0000000000004259, January 26, 2024. | DOI: 10.1097/TA.0000000000004259 

Guidelines, protocols

Why Can’t I Do Things The Way I Want?

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Most trauma centers have a book of practice protocols or guidelines. Actually, it is required by the American College of Surgeons verification standards. All centers must have a massive trauma protocol. Many have pain management or alcohol withdrawal or a number of other protocols. The question sometimes arises: why do we need another protocol? Why can’t I do it my own way?

I’ve looked at the literature, and unfortunately there’s not a lot to go on. Here are my thoughts on the value of protocols/guidelines.

In my view, there are a number of reasons why protocols need to be developed for commonly encountered issues.

  • They allow us to build in adherence to any known literature support (evidence based).
  • They help conserve resources by standardizing care orders and resource use. This means they save money!
  • They reduce confusion. Nurses do not have to guess what cares are necessary based on the specific admitting surgeon.
  • They reduce errors for the same reason. All patients receive a similar regimen, so potential errors are more easily recognized.
  • They promote team building, particularly when the protocol components involve several different services within the hospital.
  • They teach a consistent, workable approach. This is especially important to our trainees. When they graduate, they are familiar with a single, evidence based approach that will work for them in their practice.

Tomorrow, I’ll write about imaging guidelines, and how they can help avoid VOMIT (victims of medical imaging technology).

Bottom line: It’s interesting that there are so many articles about practice guidelines, but very few explaining why they are important. Although the proof is not necessarily apparent in the literature, protocol and guideline development is important for trauma programs for the reasons outlined above. But don’t develop them just so you can have an encyclopedia of fifty! Identify common problems that can benefit from the consistency they provide. It will turn out to be a very positive exercise and reap the benefits listed above.

General

Bedrest After Pediatric Liver/Spleen Injury? Really?

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A set of guidelines for management of blunt solid organ injury in children developed by the American Pediatric Surgical Association was originally published in 1999. One of the elements of the guideline was to place the child on bedrest for a period of time after the injury. Arbitrarily, this period was defined as the injury grade plus one day. So for a grade 3 spleen injury, the child would have to stay in bed for 4 days (!).

A paper published in 2013 looked at the impact of shortening this time interval. Over a 6 year period, all pediatric liver and spleen injuries from blunt trauma were identified and an abbreviated bedrest protocol was implemented. For low grade injuries (grade 1-2), children were kept in bed for 1 day, and for higher grade injuries this was extended to 2 days.

Here are the factoids:

  • 249 patients were enrolled (about 40 per year) with an average age of 10. “Bedrest was applicable for 199 patients, 80%.” Huh? Does that mean that 50 patients were excluded due to surgeon preference?
  • The organ injured was about 50:50 for spleen vs liver. Twelve children injured both.
  • Mean injury grade was 2.7, which is fairly high
  • Mean bedrest was 1.6 days, and mean hospital stay was 2.5
  • Bedrest was the limiting factor for hospital stay in 62% of cases
  • There were no delayed complications of the injury

Bottom line: Come on! Most centers don’t keep adult patients at bedrest this long, and we learned about solid organ injury management from kids! Children almost never fail nonop management, so why treat them more restrictively than adults? And have you ever tried to keep a child at bedrest? Impossible! This study is too underpowered to give real statistically valid results, but it certainly paints a good picture of what works. We recently updated our adult and pediatric protocols to eliminate bedrest and npo status. Let’s get rid of these anachronisms once and for all!

Reference: Follow up of prospective validation of an abbreviated bedrest protocol in the management of blunt spleen and liver injury in children. J Ped Surg 48(12):2437-2441, 2013.

General

Misleading Abstract Alert: Injuries Identified By Chest CT

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Here is another one of those papers that have this nicely done abstract that arrives at what seems to be a reasonable conclusion. But then you sit back and think about it. And it’s no longer so reasonable.

This study seems like it should be a good one! It’s a multi-center trial involving data from ten level I trauma centers. The research infrastructure used to collect the data and the statistical analyses for this retrospective review were sound.

Here are the factoids:

  • Of nearly 15,000 patients with blunt chest trauma, about 6,000 (40%) underwent both chest x-ray and CT
  • 25% (1,454) of these patient had new injuries discovered by the CT
  • 954 were truly occult, only being found on the CT; the remaining 500 scans found more injuries than seen on chest x-ray
  • 202 patients had major interventions (chest tube, ventilator, surgery)
  • 343 had minor interventions (admission, extended observation)
  • Chest x-ray was not very good at detecting aortic or diaphragm injury (surprise)
  • 76% of the major interventions were chest tube insertions
  • 32% of of patients with new fractures seen were hospitalized for pain control
  • None of the odds ratios reported were statistically significant

Bottom line: What could possibly go wrong? Ten trauma centers. Six thousand patients. Lots of data points. There are two major issues. First, the primary outcome was a major intervention based on the chest CT. The problem with having so many participating centers is that it is hard to figure out why they performed the interventions. Are they saying that a pneumothorax or hemothorax that was invisible on chest x-ray required a chest tube? Based on whose judgment? Unfortunately, that is a big variable. The authors admit that they did not know whether “interventions based on chest CT were truly necessary or beneficial because we did not study patient outcomes” and that the decisions for intervention “were largely made by residents (usually) or fellows.”

And the secondary outcome was admission or extended observation based on the chest CT. Yet these admissions were primarily for pain management in patients with fractures. Did the patients develop additional pain due to irradiation, or was it there all along?

So adding a chest CT greatly increases the likelihood of doing additional procedures. And it is difficult to tell (from this study) if those procedures were truly necessary. But we know that they can certainly be dangerous. If you back out all of the potentially unnecessary chest tubes and the admissions for pain that should have been admitted anyway, this study demonstrates very little additional value from CT.

A well-crafted imaging guideline will help determine which patients really need CT to identify patients with those occult injuries that are dangerous enough that they can’t be missed. The authors even conclude that “a validated decision instrument to support clinical judgment is needed.”

Related posts:

Reference: Prevalence and clinical import of thoracic injury identified by chest computed tomography but not chesty radiography in blunt trauma: multicenter prospective cohort study. Annals Emerg Med 66(6):589-600, 2015.

General

Updated Solid Organ Injury Protocol

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Over the past several days, I’ve been writing about updates to our solid organ injury protocol. It eliminates orders for bed rest and NPO diet status afterwards. After looking at our experience over the years, the number of early failures is practically zero. So how many days do you need to keep a patient in bed to make sure they have an empty stomach when they need to be whisked away to the OR. And does walking around really make your injured spleen fall apart?

The answers are none and no. So we’ve updated our protocol at Regions Hospital to reflect this. Feel free to download and modify to your heart’s content. If you want a copy of the Microsoft Publisher file, just email me!

Download the protocol here!