Tag Archives: vertebral

How Common Is BCVI, Really?

Blunt carotid and vertebral artery injuries (BCVI) are an under-appreciated problem after blunt trauma. Several screening tools have been published over the years, but they tend to be unevenly applied at individual trauma centers. I will discuss them in detail in the next section.

For the longest time, the overall incidence of BCVI was thought to be low, on the order of 1-2%. This is the number I learned years ago, and it has not really changed over time.

But how do we know for sure? Well, the group at Birmingham retrospectively reviewed every CT angiogram (CTA) of the neck they did in a recent two-year period. They did this after adopting a policy of imaging each and every one of their major blunt trauma patients for BCVI. Each patient chart was also evaluated to see if the patient met any of the criteria for the three commonly used screening systems.

During the study period, a total of 6,287 of 6,800 blunt trauma patients underwent BCVI screening with CTA of the neck. They discovered that 480 patients (7.6%) were positive for BCVI!

This is a shocking 8x higher than we expected! Why hasn’t this been obvious until now? Most likely because we were previously only aware of patients who became symptomatic. Luckily, many of these patients dodge the proverbial bullet and never exhibit any symptoms at all.

So why should we be worried? This is one of those clinical entities like blunt thoracic aortic disruption that potentially has terrible consequences if ignored. Although the number of patients who develop sequelae from their BCVI is small, suffering a stroke can be catastrophic.

Should we perform a screening study for all blunt trauma patients? Seems like overkill, or is it? Is there any way we be more selective about it?

In the next post, I’ll review the three current screening tools  used to determine which patients should receive CTA, and how good they are.

Reference: Universal screening for blunt cerebrovascular injury. J Trauma 90(2):224-231, 2021.

It’s BCVI Week!

This post will kick off a series of posts on BCVI. What is that, you ask? There seems to be some confusion as to what the acronym BCVI actually stands for. Some people believe that it means blunt cerebrovascular injury. This is not correct, because that term refers to injury to just about any vessel inside the skull.

The correct interpretation is blunt carotid and vertebral artery injury. This term refers to any portion and any combination of injury to those two pairs of vessels, from where they arise on the great vessels, all the way up into the base of the skull. Here’s a nice diagram:

Note that we will be excluding the external carotid arteries from this discussion, since injuries to them do not have any impact on the brain. They can cause troublesome bleeding, though.

These arteries are relatively protected from harm during blunt trauma. But given enough energy, bad things can happen. Fortunately, injuries to these structures are not very common, but unfortunately many trauma professionals under-appreciate their frequency and severity.

Over the next four posts, I’m going to provide an update on what we know about BCVI. I will try to tease out the true incidence, review the (multiple) screening systems, and discuss various ways to manage these injuries.

In the next post, we’ll explore the incidence of this injury. Is it truly as uncommon as we think?

Outcome After Blunt Cerebrovascular Injury (BCVI)

Blunt injuries to the carotid and vertebral arteries are not as uncommon as we used to think. Unfortunately, there’s a lot of controversy surrounding everything about them: screening, management, and outcome. A paper just out detailed outcomes in a (relatively) large series of these patients. 

As expected with this rare injury, it’s a retrospective study. A busy Level I center identified 222 patients with 263 BCVIs over a 4 ½ year period. Twenty four died before discharge and 11 afterwards. Of the remaining patients, only 74 could be located and only 68 could be persuaded to complete an interview and evaluation of their functional status. Functional Independence and Functional Activity Measurements were assessed (FIM/FAM).

Pertinent findings were:

  • 8 patients suffered a stroke during their initial hospital stay (5 were present on arrival in the ED)
  • 5 additional patients had a stroke after discharge
  • Only 20% reached the maximum FIM/FAM scores, even including patients who did not have a stroke
  • Patients with stroke had a significantly lower FIM/FAM
  • There was no difference in FIM/FAM in patients with carotid vs vertebral injury

Bottom Line: Even though it is limited, this is one of the best studies we will see on BCVI because it’s an uncommon problem at most centers. The most important fact here is that the stroke rate was 19% despite discharge on antiplatelet or anticoagulant medications. And if stroke occurs, it causes significant functional problems, as expected. It’s critically important that this injury be screened and identified appropriately, then given appropriate prophylaxis. More on this tomorrow.

Related posts:

Reference: Functional outcomes following blunt cerebrovascular injury. J Trauma 74(4):955-960, 2013.

Carotid and Vertebral Artery Injury From Blunt Trauma

Blunt injury to the carotid or vertebral arteries (BCVI) is relatively uncommon, but potentially very deadly. Up to 2% of patients with high energy blunt trauma suffer this injury. Many are not diagnosed until the patient has ischemic symptoms or a stroke. However, more aggressive screening has shown a higher incidence that previously thought and may allow intervention before neurologic injury occurs.

Recently, a series of 222 patients with 263 BCVI was retrospectively reviewed, with an eye toward effectiveness of interventions. A total of 29 strokes occurred in the hospital in these patients, but only 7 of these occurred after diagnosis of the BCVI. Mortality was much higher in the stroke group (34% vs 7%). The authors looked at both medical and interventional therapies.

This paper identified the following items:

  • Car crash was the most common mechanism of injury (81%)
  • Vertebral arterial injury was slightly more common than carotid artery BUT
  • Women were much more likely to sustain a carotid injury
  • Older patients were more likely to have a vertebral injury

These authors found that CT angio was not sufficiently sensitive to identify all BCVI. They recommend a formal 4-vessel arteriogram in patients with a negative CT angio who have significant risk factors (unexplained neurologic deficit, Horner’s syndrome, LeFort II or III injury, cervical spine injury, soft tissue injury of the neck).

If a BCVI is identified, the patient should be heparinized until all other injuries are definitively managed. At that point, they should be preloaded with clopidogrel and aspirin and a repeat arteriogram should be performed. Endovascular stenting using a bare metal stent should be performed when possible because it results in the lowest stroke rate and requires the shortest duration of anti-platelet therapies. Patients then continue on aspirin and clopidogrel for an appropriate period of time.

To download the algorithm used by the authors, click here.

Reference: Optimal outcomes for patients with blunt cerebrovascular injury (BCVI): tailoring treatment to the lesion. J Am Coll Surg 212(4):549-559, 2011.