Category Archives: protocols

The CIWA Protocol Demystified

What exactly is the CIWA protocol?

It is a tool used commonly in the US that helps clinicians assess and treat potential alcohol withdrawal. A significant amount of injury in this country is due to the overuse of alcohol. A subset of these patients are admitted and do not have access to alcohol. They may begin to withdraw within a few days, and this condition can lead to dangerous complications.

The Clinical Institute Withdrawal Assessment measures 10 items that are associated with withdrawal:

  • Nausea / vomiting
  • Anxiety
  • Paroxysmal sweats
  • Tactile disturbances (itching, bugs crawling on skin, etc)
  • Visual disturbances
  • Tremors
  • Agitation
  • Orientation
  • Auditory disturbances
  • Headache

All items are measured on a scale of 0-7 with the exception of orientation, which uses a scale of 0-4. All subscores are tallied to arrive at the final score.

The total score is used to determine whether benzodiazepines should be given to ameliorate symptoms or avoid seizures. Typically, a threshold is selected (8 or 10) and no medications are needed as long as the patient is under it. Once it is exceeded, graduated doses of lorazepam or diazepam are given and vital signs and CIWA scores are repeated regularly. The protocol is discontinued once the patient has three determinations that are under the threshold.

The individual dosing scale and monitoring routine varies by hospital. Look at your hospital policy manual to get specifics for your institution.

For a copy of the CIWA scoring criteria, click here.

Tomorrow, precautions when using the CIWA protocol.

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Acute Ethanol Intoxication And The Banana Bag

It’s one of those time honored treatments that most hospital-based providers are familiar with. The banana bag, reserved for intoxicated patients presenting to the ED or admitted to the hospital. They’ve been around so long, we just take them for granted. But like most things that have become dogmatic, they are due to be questioned from time to time.

A banana bag is a proprietary mix of “good” stuff, including electrolytes and vitamins, especially thiamine and magnesium. The exact content varies from hospital to hospital. Thiamine and other B vitamins give the resulting solution the characteristic color, hence the term “banana.”

Does it actually do good things like ward off Wernicke’s encephalopathy and megaloblastic anemia? A paper from Jacobi Medical Center in the Bronx prospectively evaluated a series of intoxicated people entering their ED. They drew vitamin B12, folate, and thiamine levels to see if they were deficient enough to even need vitamin supplementation.

Interesting findings:

  • These folks (only 77 patients) were very drunk! Average BAC was 280mg/dL.
  • Vitamin B12 and folate levels were not critically low in any patient
  • Thiamine was low in 15% of patients, but none had clinical evidence of a deficiency
  • Later review of prior visits revealed that some patients with low levels had received a previous banana bag within 1 month. Did it do any good?

Bottom line: Most of our intoxicated patients are not vitamin deficient, and don’t need supplementation. The real kicker is that  we almost never really try to find out if the patient might be a chronic abuser and potentially at risk. We just hang the bag. Remember, everything we do in medicine has a potential downside. And if the patient really doesn’t need a banana bag in the first place, there is no benefit to balance that risk. The next time you ask for that little yellow bag, think again!

Reference: Vitamin deficiencies in acutely intoxicated patients in the ED. Am J Emerg Med 26(7):729-795, 2008.

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Giving Alcohol To Prevent Alcohol Withdrawal??

Alcohol abuse is a major problem worldwide, and provides trauma professionals with a never-ending stream of patients to take care of. A few of our patients partake so frequently that they are at risk for complications when they are forced to stop (e.g. admitted to the hospital).

In days gone by, one of the possible treatments for alcohol withdrawal was actual administration of ethanol in the hospital, by mouth or sometimes IV (!). For the most part, this has fallen by the wayside. However, I do get questions from readers about it from time to time, and I assume that this still happens at some hospitals. And I know of a few hospitals that still have beer on the formulary!

So what’s the answer? There is enough literature out there to convincingly say that the practice should be abandoned. Here are some factoids for you:

  • Benzodiazepines are now the first-line treatment for withdrawal
  • Benzos have anticonvulsant properties, which ethanol does not
  • Benzos cause less respiratory depression than ethanol when dosed properly
  • Using a CIWA protocol early minimizes over-medication events and can prevent progression to more serious withdrawal
  • Lorazepam is a good choice because its metabolism is minimally affected by liver dysfunction
  • The use of ethanol to treat withdrawal condones alcohol abuse and does not promote behavioral change or treatment

Bottom line: Don’t reach for the bottle when trying to prevent or treat alcohol withdrawal syndrome. Monitor at-risk patients closely, adopt a finely-tuned CIWA protocol (see below), and aggressively refer to treatment after your patient recovers. 

Reference: Ethanol for alcohol withdrawal: end of an era. J Trauma 74(3):925-931, 2013.

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The Value of Protocols in Trauma

Most trauma centers have a book of practice protocols or guideleines. Actually, it is required by the American College of Surgeons verification standards. All centers must have a massive trauma protocol. Many have pain management or alcohol withdrawal or a number of other protocols. The question sometimes arises: why do we need another protocol? Can we show some benefit to using a protocol?

I’ve looked at the literature, and unfortunately there’s not a lot to go on. Here are my thoughts on the value of protocols.

In my view, there are a number of reasons why protocols need to be developed for commonly encountered issues.

  • They allow us to build in adherence to any known practice guidelines or literature.
  • They help conserve resources by standardizing care orders and resource use.
  • They reduce confusion. Nurses do not have to guess what cares are necessary based on the specific admitting surgeon.
  • They reduce errors for the same reason. All patients receive a similar regimen, so potential errors are more easily recognized.
  • They promote team building, particularly when the protocol components involve several different services within the hospital.
  • They teach a consistent, workable approach to our trainees. When they graduate, they are familiar with a single, evidence based approach that will work for them in their practice.

A number of years ago, we implemented a solid organ injury protocol here at Regions Hospital. I noted that there were large variations in simple things like time at bedrest, frequency of blood draws, how long the patient was kept without food and whether angiography should be considered. Once we implemented the protocol, patients were treated much more consistently and we found that costs were reduced by over $1000 per patient. Since we treat about 200 of these patients per year, the hospital saved quite a bit of money! And our blunt trauma radiographic imaging protocol has significantly reduced patient exposure to radiation.

Bottom line: Although the proof is not necessarily apparent in the literature, protocol development is important for trauma programs for the reasons outlined above. But don’t develop them for their own sake. Identify common problems that can benefit from consistency. It will turn out to be a very positive exercise and reap the benefits listed above.

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Acute Ethanol Intoxication And The Banana Bag

It’s one of those time honored treatments that most hospital-based providers are familiar with. The banana bag, reserved for intoxicated patients presenting to the ED or admitted to the hospital. They’ve been around so long, we just take them for granted. But like most things that have become dogmatic, they are due to be questioned from time to time.

image

A banana bag is a proprietary mix of “good” stuff, including electrolytes and vitamins, especially thiamine and magnesium. The exact content varies from hospital to hospital. Thiamine and other B vitamins give the resulting solution the characteristic color, hence the term “banana.”

Does it actually do good things like ward off Wernicke’s encephalopathy and megaloblastic anemia? A paper from Jacobi Medical Center in the Bronx prospectively evaluated a series of intoxicated people entering their ED. They drew vitamin B12, folate, and thiamine levels to see if they were deficient enough to even need vitamin supplementation.

Here are the factoids:

  • These folks (only 77 patients) were very drunk! Average BAC was 280mg/dL.
  • Vitamin B12 and folate levels were not critically low in any patient
  • Thiamine was low in 15% of patients, but none had clinical evidence of a deficiency
  • Later review of prior visits revealed that some patients with low levels had received a previous banana bag within 1 month. Did it do any good?

Bottom line: Most of our intoxicated patients are not vitamin deficient, and don’t need supplementation. The real kicker is that we almost never really try to find out if the patient might be a chronic abuser and potentially at risk. We just hang the bag. Remember, everything we do in medicine has a potential downside. And if the patient really doesn’t need a banana bag in the first place, there is no benefit to balance that risk. The next time you ask for that little yellow bag, think again!

Reference: Vitamin deficiencies in acutely intoxicated patients in the ED. Am J Emerg Med 26(7):729-795, 2008.

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