Category Archives: History

Trauma 20 Years Ago: Continuous Epidural Analgesia for Rib Fractures

Rib fractures are painful, and lots of rib fractures not only hurt, but can lead to complications or death. We take for granted all the modalities we now have for pain relief with rib fractures:

  • IV narcotics
  • epidural analgesia
  • rib blocks
  • intrapleural analgesia
  • lidocaine patches
  • fracture fixation techniques
  • and more!

In April 1991, we were still trying to figure out if epidural analgesia was any better than IV narcotics. A small prospective study of 32 patients who were awake and alert and had at least 3 rib fractures were given either IV or epidural fentanyl. The drug was administered as an initial bolus, followed by a continuous infusion. A visual analog pain scale was used for titration.

Vital capacity increased significantly in both groups. Epidural analgesia also led to an improvement in maximum inspiratory pressure (which we now know as NIF). IV analgesia led to somewhat troubling increases in pCO2 and decreases in pO2, whereas epidural administration did not. Pain relief was better with the epidural, while side effects were similar.

The authors concluded that epidural analgesia offers several advantages over IV, and stated that it should be the preferred method for patients at high risk for complications following multiple rib fractures. This paper started us on the path to using the epidural for pain management with significant rib fractures.

Reference: Prospective evaluation of epidural and intravenous administration of fentanyl for pain control and restoration of ventilatory function following multiple rib fractures. J Trauma 31(4):443-451, 1991.

Trauma 20 Years Ago: Early vs Delayed Femur Fixation

Today, we take for granted that fixing fractures early is a good thing. However, this topic was still under debate 20 years ago. Trauma care has always been prioritized, with life-threatening injuries taking precedence. It was very common for major trauma patients to undergo operation for their torso injuries, and then be deemed “too unstable” to undergo repair of their extremities.

Weigelt et al reported decreased pulmonary complications with early fixation in 1989. A study published in July 1990 looked at 121 early vs 218 late femur fixations with respect to more concrete outcomes. The patients were similar with respect to hypotension, transfusions and associated injuries.

They found that delayed fixation increased pulmonary shunt, especially in patients with more severe injuries, and increased the incidence of pneumonia in older patients. It also resulted in more ICU days and a significantly longer hospital stay in the more severely injured group.

This paper was a valuable addition that began to shape our appreciation for the importance of early fixation of most fractures. Major trauma makes patients sick, but they are in the best condition they will be in for weeks at the time they arrive at the hospital. This makes it the ideal time to take care of injuries that may otherwise contribute to morbidity and mortality.

Reference: Fabian et al. Improved outcome with femur fractures: early vs delayed fixation. J Trauma 30(7):792, 1990.